主要讲述的是在上古世界人妖共存在三界之中，出现了一个妖医馆，这个医馆，只医妖不医人，相传这里的掌柜医师红娘风情万种，用的是人皮人面一身吃蛤蟆精，喝人血，这令人们闻风丧胆。在原本风平浪静的医馆里，却因为一名不速之客的书生金志坚的到来而陷入了重重困难危机当中，这位书生竟然神奇的怀了孕，不巧的是，红娘本欲为其所生，曲奇魔丸心头血，方能破解红娘自身命格的短缺和缺陷，不想经过几日对魔丸和书生的悉心照料一妖一人经产生了情愫，红娘心软，决定放走魔丸，却遭遇玄甲门围堵，在打斗的过程中，红娘知道这一切原来都是掌门的计谋，他想用魔玩的心头血培养嗜血菱花，在以吸食妖族血脉为自身严重，从而达到长生不老，红娘陷入了绝望，把他们都给杀了

The main story is that in the ancient world, humans and monsters coexisted in the Three Realms, and there appeared a monster doctor's clinic, which only healed monsters but not humans. , according to legend, the shopkeeper, the doctor, the matchmaker, is very charming. She uses human skin and human face to eat toad essence and drink human blood. This makes people frightened. In the hospital, which was originally calm and peaceful, it fell into many difficulties and crises because of the arrival of an unexpected visitor, the scholar Jin Zhijian. The scholar unexpectedly became pregnant miraculously. Qi Mowan's hard work can solve the shortage and flaws of Hongniang's own fate. After a few days of caring for Magic Pill and the scholar, the demon has developed feelings. The matchmaker decided to let Magic Pill go, but encountered Xuanjia During the fight, Hongniang knew that all of this was a trick of the headmaster. He wanted to use Mowan's heart blood to cultivate the bloodthirsty water chestnut flower. He wanted to drink the blood of the monster race as his own responsibility, so as to achieve immortality. , Hong Niang fell into despair and killed them all